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mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion

Liver triacylglycerol (TAG) synthesis and secretion are closely linked to nutrient availability. After a meal, hepatic TAG formation from fatty acids is decreased, largely due to a reduction in circulating free fatty acids (FFA). Despite the postprandial decrease in FFA-driven esterification and oxi...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Quinn, William J., Wan, Min, Shewale, Swapnil V., Gelfer, Rebecca, Rader, Daniel J., Birnbaum, Morris J., Titchenell, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663357/
https://ncbi.nlm.nih.gov/pubmed/29035283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96036
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