Good Manufacturing Practice-Compliant Production and Lot-Release of Ex Vivo Expanded Regulatory T Cells As Basis for Treatment of Patients with Autoimmune and Inflammatory Disorders

In recent years, the exploration of regulatory T cell (Treg)-based cellular therapy has become an attractive strategy to ameliorate inflammation and autoimmunity in various clinical settings. The main obstacle to the clinical application of Treg in human is their low number circulating in peripheral...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wiesinger, Manuel, Stoica, Diane, Roessner, Susanne, Lorenz, Carmen, Fischer, Anika, Atreya, Raja, Neufert, Clemens F., Atreya, Imke, Scheffold, Alexander, Schuler-Thurner, Beatrice, Neurath, Markus F., Schuler, Gerold, Voskens, Caroline J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662555/
https://ncbi.nlm.nih.gov/pubmed/29123521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01371
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