Good Manufacturing Practice-Compliant Production and Lot-Release of Ex Vivo Expanded Regulatory T Cells As Basis for Treatment of Patients with Autoimmune and Inflammatory Disorders

In recent years, the exploration of regulatory T cell (Treg)-based cellular therapy has become an attractive strategy to ameliorate inflammation and autoimmunity in various clinical settings. The main obstacle to the clinical application of Treg in human is their low number circulating in peripheral...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Wiesinger, Manuel, Stoica, Diane, Roessner, Susanne, Lorenz, Carmen, Fischer, Anika, Atreya, Raja, Neufert, Clemens F., Atreya, Imke, Scheffold, Alexander, Schuler-Thurner, Beatrice, Neurath, Markus F., Schuler, Gerold, Voskens, Caroline J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662555/
https://ncbi.nlm.nih.gov/pubmed/29123521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01371
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