Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation

Aims: Many progressive neurological disorders, including Alzheimer's disease (AD), Huntington's disease, and Parkinson's disease (PD), are characterized by accumulation of insoluble protein aggregates. In prospective trials, the cyclooxygenase inhibitor aspirin (acetylsalicylic acid)...

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Détails bibliographiques
Publié dans:Antioxid Redox Signal
Auteurs principaux: Ayyadevara, Srinivas, Balasubramaniam, Meenakshisundaram, Kakraba, Samuel, Alla, Ramani, Mehta, Jawahar L., Shmookler Reis, Robert J.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2017
Sujets:
Original Research Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661865/
https://ncbi.nlm.nih.gov/pubmed/28537433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6978
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