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PIP(3)-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans
Class-I phosphatidylinositol 3-kinase (PI3K(I)) converts phosphatidylinositol 4,5-bisphosphate (PIP(2)) to phosphatidylinositol 3,4,5-triphosphate (PIP(3)). PIP(3) comprises two fatty-acid chains that embed in lipid-bilayer membranes, joined by glycerol to inositol triphosphate. Proteins with domain...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5226477/ https://ncbi.nlm.nih.gov/pubmed/27429199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10549 |
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