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Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome-blocking complexes
Age-dependent neurodegenerative diseases progressively form aggregates containing both shared components (e.g., TDP-43, phosphorylated tau) and proteins specific to each disease. We investigated whether diverse neuropathies might have additional aggregation-prone proteins in common, discoverable by...
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| Publicado no: | Aging Cell |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326912/ https://ncbi.nlm.nih.gov/pubmed/25510159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12296 |
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