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Preparation, pharmacokinetics, tissue distribution and antitumor effect of sorafenib-incorporating nanoparticles in vivo

Sorafenib is a molecularly targeted drug used for treating hepatocellular carcinoma. However, sorafenib may affect the function of normal hepatocytes, and the clinical application of sorafenib is limited due to its adverse effects. The aim of the current study was to improve the effectiveness of sor...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Sheng, Xia, Huang, Tao, Qin, Jianmin, Li, Qi, Wang, Weiwei, Deng, Liandong, Dong, Anjie
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661419/
https://ncbi.nlm.nih.gov/pubmed/29113262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6934
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