Preparation of polylactide-co-glycolide nanoparticles incorporating celecoxib and their antitumor activity against brain tumor cells

BACKGROUND: Celecoxib, a cyclo-oxygenase (COX)-2 inhibitor, has been reported to mediate growth inhibitory effects and to induce apoptosis in various cancer cell lines. In this study, we examined the potential effects of celecoxib on glioma cell proliferation, migration, and inhibition of COX-2 expr...

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Hlavní autoři: Kim, Tae-Ho, Jeong, Young-Il, Jin, Shu-Guang, Pei, Jian, Jung, Tae-Young, Moon, Kyung-Sub, Kim, In-Young, Kang, Sam-Suk, Jung, Shin
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2011
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218576/
https://ncbi.nlm.nih.gov/pubmed/22114493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S19497
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