Preparation of polylactide-co-glycolide nanoparticles incorporating celecoxib and their antitumor activity against brain tumor cells

BACKGROUND: Celecoxib, a cyclo-oxygenase (COX)-2 inhibitor, has been reported to mediate growth inhibitory effects and to induce apoptosis in various cancer cell lines. In this study, we examined the potential effects of celecoxib on glioma cell proliferation, migration, and inhibition of COX-2 expr...

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Detalhes bibliográficos
Main Authors: Kim, Tae-Ho, Jeong, Young-Il, Jin, Shu-Guang, Pei, Jian, Jung, Tae-Young, Moon, Kyung-Sub, Kim, In-Young, Kang, Sam-Suk, Jung, Shin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218576/
https://ncbi.nlm.nih.gov/pubmed/22114493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S19497
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