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Regulation of Nephron Progenitor Cell Self-Renewal by Intermediary Metabolism

Nephron progenitor cells (NPCs) show an age-dependent capacity to balance self-renewal with differentiation. Older NPCs (postnatal day 0) exit the progenitor niche at a higher rate than younger (embryonic day 13.5) NPCs do. This behavior is reflected in the transcript profiles of young and old NPCs....

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Liu, Jiao, Edgington-Giordano, Francesca, Dugas, Courtney, Abrams, Anna, Katakam, Prasad, Satou, Ryousuke, Saifudeen, Zubaida
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661282/
https://ncbi.nlm.nih.gov/pubmed/28754792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016111246
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