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Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles

Nephron progenitor cells (NPCs) are Six2-positive metanephric mesenchyme cells, which undergo self-renewal and differentiation to give rise to nephrons until the end of nephrogenesis. Histone deacetylases (HDACs) are a group of epigenetic regulators that control cell fate, but their role in balancin...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Liu, Hongbing, Chen, Shaowei, Yao, Xiao, Li, Yuwen, Chen, Chao-Hui, Liu, Jiao, Saifudeen, Zubaida, El-Dahr, Samir S.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001373/
https://ncbi.nlm.nih.gov/pubmed/29712641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.153619
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