Lanean...

p53 enables metabolic fitness and self-renewal of nephron progenitor cells

Contrary to its classic role in restraining cell proliferation, we demonstrate here a divergent function of p53 in the maintenance of self-renewal of the nephron progenitor pool in the embryonic mouse kidney. Nephron endowment is regulated by progenitor availability and differentiation potential. Co...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Development
Egile Nagusiak: Li, Yuwen, Liu, Jiao, Li, Wencheng, Brown, Aaron, Baddoo, Melody, Li, Marilyn, Carroll, Thomas, Oxburgh, Leif, Feng, Yumei, Saifudeen, Zubaida
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378244/
https://ncbi.nlm.nih.gov/pubmed/25804735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.111617
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!