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p53 enables metabolic fitness and self-renewal of nephron progenitor cells
Contrary to its classic role in restraining cell proliferation, we demonstrate here a divergent function of p53 in the maintenance of self-renewal of the nephron progenitor pool in the embryonic mouse kidney. Nephron endowment is regulated by progenitor availability and differentiation potential. Co...
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| Publicado no: | Development |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4378244/ https://ncbi.nlm.nih.gov/pubmed/25804735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.111617 |
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