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p53 enables metabolic fitness and self-renewal of nephron progenitor cells

Contrary to its classic role in restraining cell proliferation, we demonstrate here a divergent function of p53 in the maintenance of self-renewal of the nephron progenitor pool in the embryonic mouse kidney. Nephron endowment is regulated by progenitor availability and differentiation potential. Co...

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Detaylı Bibliyografya
Yayımlandı:Development
Asıl Yazarlar: Li, Yuwen, Liu, Jiao, Li, Wencheng, Brown, Aaron, Baddoo, Melody, Li, Marilyn, Carroll, Thomas, Oxburgh, Leif, Feng, Yumei, Saifudeen, Zubaida
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378244/
https://ncbi.nlm.nih.gov/pubmed/25804735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.111617
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