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Histone Deacetylase Inhibitors Are Protective in Acute but Not in Chronic Models of Ototoxicity
Previous studies have reported that modification of histones alters aminoglycoside-induced hair cell death and hearing loss. In this study, we investigated three FDA-approved histone deacetylase (HDAC) inhibitors (vorinostat/SAHA, belinostat, and panobinostat) as protectants against aminoglycoside-i...
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| Publicado no: | Front Cell Neurosci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5660723/ https://ncbi.nlm.nih.gov/pubmed/29114207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00315 |
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