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APOLs with low pH dependence can kill all African trypanosomes

The primate-specific serum protein apolipoprotein L1 (APOL1) is the only secreted member of a family of cell death promoting proteins1–4. APOL1 kills the bloodstream parasite Trypanosoma brucei brucei, but not the human sleeping sickness agents T.b. rhodesiense and T.b. gambiense3. We considered the...

詳細記述

保存先:
書誌詳細
出版年:Nat Microbiol
主要な著者: Fontaine, Frédéric, Lecordier, Laurence, Vanwalleghem, Gilles, Uzureau, Pierrick, Van Reet, Nick, Fontaine, Martina, Tebabi, Patricia, Vanhollebeke, Benoit, Büscher, Philippe, Pérez-Morga, David, Pays, Etienne
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660622/
https://ncbi.nlm.nih.gov/pubmed/28924146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-017-0034-1
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