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APOLs with low pH dependence can kill all African trypanosomes
The primate-specific serum protein apolipoprotein L1 (APOL1) is the only secreted member of a family of cell death promoting proteins1–4. APOL1 kills the bloodstream parasite Trypanosoma brucei brucei, but not the human sleeping sickness agents T.b. rhodesiense and T.b. gambiense3. We considered the...
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| Publicado no: | Nat Microbiol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5660622/ https://ncbi.nlm.nih.gov/pubmed/28924146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-017-0034-1 |
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