The K186E Amino Acid Substitution in the Canine Influenza Virus H3N8 NS1 Protein Restores Its Ability To Inhibit Host Gene Expression

Canine influenza viruses (CIVs) are the causative agents of canine influenza, a contagious respiratory disease in dogs, and include the equine-origin H3N8 and the avian-origin H3N2 viruses. Influenza A virus (IAV) nonstructural protein 1 (NS1) is a virulence factor essential for counteracting the in...

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Vydáno v:J Virol
Hlavní autoři: Nogales, Aitor, Chauché, Caroline, DeDiego, Marta L., Topham, David J., Parrish, Colin R., Murcia, Pablo R., Martínez-Sobrido, Luis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660486/
https://ncbi.nlm.nih.gov/pubmed/28835506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00877-17
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