The K186E Amino Acid Substitution in the Canine Influenza Virus H3N8 NS1 Protein Restores Its Ability To Inhibit Host Gene Expression

Canine influenza viruses (CIVs) are the causative agents of canine influenza, a contagious respiratory disease in dogs, and include the equine-origin H3N8 and the avian-origin H3N2 viruses. Influenza A virus (IAV) nonstructural protein 1 (NS1) is a virulence factor essential for counteracting the in...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Nogales, Aitor, Chauché, Caroline, DeDiego, Marta L., Topham, David J., Parrish, Colin R., Murcia, Pablo R., Martínez-Sobrido, Luis
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660486/
https://ncbi.nlm.nih.gov/pubmed/28835506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00877-17
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