The K186E Amino Acid Substitution in the Canine Influenza Virus H3N8 NS1 Protein Restores Its Ability To Inhibit Host Gene Expression

Canine influenza viruses (CIVs) are the causative agents of canine influenza, a contagious respiratory disease in dogs, and include the equine-origin H3N8 and the avian-origin H3N2 viruses. Influenza A virus (IAV) nonstructural protein 1 (NS1) is a virulence factor essential for counteracting the in...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Nogales, Aitor, Chauché, Caroline, DeDiego, Marta L., Topham, David J., Parrish, Colin R., Murcia, Pablo R., Martínez-Sobrido, Luis
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
Предметы:
Virus-Cell Interactions
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660486/
https://ncbi.nlm.nih.gov/pubmed/28835506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00877-17
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