Dynamic changes in eIF4F-mRNA interactions revealed by global analyses of environmental stress responses

BACKGROUND: Translation factors eIF4E and eIF4G form eIF4F, which interacts with the messenger RNA (mRNA) 5′ cap to promote ribosome recruitment and translation initiation. Variations in the association of eIF4F with individual mRNAs likely contribute to differences in translation initiation frequen...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Costello, Joseph L., Kershaw, Christopher J., Castelli, Lydia M., Talavera, David, Rowe, William, Sims, Paul F. G., Ashe, Mark P., Grant, Christopher M., Hubbard, Simon J., Pavitt, Graham D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660459/
https://ncbi.nlm.nih.gov/pubmed/29078784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1338-4
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