Integrated multi-omics analyses reveal the pleiotropic nature of the control of gene expression by Puf3p

The PUF family of RNA-binding proteins regulate gene expression post-transcriptionally. Saccharomyces cerevisiae Puf3p is characterised as binding nuclear-encoded mRNAs specifying mitochondrial proteins. Extensive studies of its regulation of COX17 demonstrate its role in mRNA decay. Using integrate...

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Publicado no:Sci Rep
Main Authors: Kershaw, Christopher J., Costello, Joseph L., Talavera, David, Rowe, William, Castelli, Lydia M., Sims, Paul F. G., Grant, Christopher M., Ashe, Mark P., Hubbard, Simon J., Pavitt, Graham D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4616039/
https://ncbi.nlm.nih.gov/pubmed/26493364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15518
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