Margination and stretching of von Willebrand factor in the blood stream enable adhesion

The protein von Willebrand factor (VWF) is essential in primary hemostasis, as it mediates platelet adhesion to vessel walls. VWF retains its compact (globule-like) shape in equilibrium due to internal molecular associations, but is able to stretch when a high enough shear stress is applied. Even th...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Rack, Kathrin, Huck, Volker, Hoore, Masoud, Fedosov, Dmitry A., Schneider, Stefan W., Gompper, Gerhard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660260/
https://ncbi.nlm.nih.gov/pubmed/29079767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14346-4
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