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Margination and stretching of von Willebrand factor in the blood stream enable adhesion
The protein von Willebrand factor (VWF) is essential in primary hemostasis, as it mediates platelet adhesion to vessel walls. VWF retains its compact (globule-like) shape in equilibrium due to internal molecular associations, but is able to stretch when a high enough shear stress is applied. Even th...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5660260/ https://ncbi.nlm.nih.gov/pubmed/29079767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14346-4 |
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