Sitagliptin reduces inflammation, fibrosis and preserves diastolic function in a rat model of heart failure with preserved ejection fraction

BACKGROUND AND PURPOSE: Heart failure with preserved ejection fraction (HFpEF) is a systemic syndrome driven by co‐morbidities, and its pathophysiology is poorly understood. Several studies suggesting that dipeptidyl peptidase 4 (DPP4) might be involved in the pathophysiology of heart failure have p...

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發表在:Br J Pharmacol
Main Authors: Esposito, Grazia, Cappetta, Donato, Russo, Rosa, Rivellino, Alessia, Ciuffreda, Loreta Pia, Roviezzo, Fiorentina, Piegari, Elena, Berrino, Liberato, Rossi, Francesco, De Angelis, Antonella, Urbanek, Konrad
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2017
主題:
Themed Section: Research Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659996/
https://ncbi.nlm.nih.gov/pubmed/27922176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13686
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