Cardioprotective effects of miR-34a silencing in a rat model of doxorubicin toxicity

Cardiotoxicity remains a serious problem in anthracycline-treated oncologic patients. Therapeutic modulation of microRNA expression is emerging as a cardioprotective approach in several cardiovascular pathologies. MiR-34a increased in animals and patients exposed to anthracyclines and is involved in...

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Published in:Sci Rep
Main Authors: Piegari, Elena, Cozzolino, Anna, Ciuffreda, Loreta Pia, Cappetta, Donato, De Angelis, Antonella, Urbanek, Konrad, Rossi, Francesco, Berrino, Liberato
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378226/
https://ncbi.nlm.nih.gov/pubmed/32704131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69038-3
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