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Human Pyrimidine Nucleotide Biosynthesis as a Target for Antiviral Chemotherapy

The development of broad-spectrum, host-acting antiviral therapies remains an important but elusive goal in anti-infective drug discovery. To replicate efficiently, viruses not only depend on their hosts for an adequate supply of pyrimidine nucleotides, but also up-regulate pyrimidine nucleotide bio...

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Podrobná bibliografie
Vydáno v:Curr Opin Biotechnol
Hlavní autoři: Okesli, Ayse, Khosla, Chaitan, Bassik, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659961/
https://ncbi.nlm.nih.gov/pubmed/28458037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2017.03.010
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