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Activation of γ2-AMPK Suppresses Ribosome Biogenesis and Protects Against Myocardial Ischemia/Reperfusion Injury

RATIONALE: AMP-activated protein kinase (AMPK) is a heterotrimeric protein that plays an important role in energy homeostasis and cardioprotection. Two isoforms of each subunit are expressed in the heart but the isoform-specific function of AMPK remains unclear. OBJECTIVE: We sought to determine the...

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Publicat a:Circ Res
Autors principals: Cao, Yang, Bojjireddy, Naveen, Kim, Maengjo, Li, Tao, Zhai, Peiyong, Nagarajan, Narayani, Sadoshima, Junichi, Palmiter, Richard D., Tian, Rong
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659937/
https://ncbi.nlm.nih.gov/pubmed/28835357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.311159
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