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Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury

Although autophagy is generally protective, uncontrolled or excessive activation of autophagy can be detrimental. However, it is often difficult to distinguish death by autophagy from death with autophagy, and whether autophagy contributes to death in cardiomyocytes (CMs) is still controversial. Exc...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Nah, Jihoon, Zhai, Peiyong, Huang, Chun-Yang, Fernández, Álvaro F., Mareedu, Satvik, Levine, Beth, Sadoshima, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260042/
https://ncbi.nlm.nih.gov/pubmed/32364533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI132366
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