DNA Sequence Constraints Define Functionally Active Steroid Nuclear Receptor Binding Sites in Chromatin

Gene regulatory programs are encoded in the sequence of the DNA. Since the completion of the Human Genome Project, millions of gene regulatory elements have been identified in the human genome. Understanding how each of those sites functionally contributes to gene regulation, however, remains a chal...

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Bibliografski detalji
Izdano u:Endocrinology
Glavni autori: Coons, Laurel A., Hewitt, Sylvia C., Burkholder, Adam B., McDonnell, Donald P., Korach, Kenneth S.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2017
Teme:
Special Section: Targeting and Regulation of Hormone Signaling
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659708/
https://ncbi.nlm.nih.gov/pubmed/28977594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00468
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