DNA Sequence Constraints Define Functionally Active Steroid Nuclear Receptor Binding Sites in Chromatin

Gene regulatory programs are encoded in the sequence of the DNA. Since the completion of the Human Genome Project, millions of gene regulatory elements have been identified in the human genome. Understanding how each of those sites functionally contributes to gene regulation, however, remains a chal...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Coons, Laurel A., Hewitt, Sylvia C., Burkholder, Adam B., McDonnell, Donald P., Korach, Kenneth S.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Special Section: Targeting and Regulation of Hormone Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659708/
https://ncbi.nlm.nih.gov/pubmed/28977594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00468
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