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Dipeptidyl Peptidase-4 Inhibition With Saxagliptin Ameliorates Angiotensin II–Induced Cardiac Diastolic Dysfunction in Male Mice

Activation of the renin–angiotensin–aldosterone system is common in hypertension and obesity and contributes to cardiac diastolic dysfunction, a condition for which no treatment currently exists. In light of recent reports that antihyperglycemia incretin enhancing dipeptidyl peptidase (DPP)-4 inhibi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Endocrinology
Prif Awduron: Brown, Scott M., Smith, Cassandra E., Meuth, Alex I., Khan, Maloree, Aroor, Annayya R., Cleeton, Hannah M., Meininger, Gerald A., Sowers, James R., DeMarco, Vincent G., Chandrasekar, Bysani, Nistala, Ravi, Bender, Shawn B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659692/
https://ncbi.nlm.nih.gov/pubmed/28977602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00416
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