Dipeptidyl peptidase-4 inhibition with linagliptin prevents western diet-induced vascular abnormalities in female mice

BACKGROUND: Vascular stiffening, a risk factor for cardiovascular disease, is accelerated, particularly in women with obesity and type 2 diabetes. Preclinical evidence suggests that dipeptidylpeptidase-4 (DPP-4) inhibitors may have cardiovascular benefits independent of glycemic lowering effects. Re...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Manrique, Camila, Habibi, Javad, Aroor, Annayya R., Sowers, James R., Jia, Guanghong, Hayden, Melvin R., Garro, Mona, Martinez-Lemus, Luis A., Ramirez-Perez, Francisco I., Klein, Thomas, Meininger, Gerald A., DeMarco, Vincent G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938903/
https://ncbi.nlm.nih.gov/pubmed/27391040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-016-0414-5
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