Dipeptidyl Peptidase-4 Inhibition With Saxagliptin Ameliorates Angiotensin II–Induced Cardiac Diastolic Dysfunction in Male Mice

Activation of the renin–angiotensin–aldosterone system is common in hypertension and obesity and contributes to cardiac diastolic dysfunction, a condition for which no treatment currently exists. In light of recent reports that antihyperglycemia incretin enhancing dipeptidyl peptidase (DPP)-4 inhibi...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Brown, Scott M., Smith, Cassandra E., Meuth, Alex I., Khan, Maloree, Aroor, Annayya R., Cleeton, Hannah M., Meininger, Gerald A., Sowers, James R., DeMarco, Vincent G., Chandrasekar, Bysani, Nistala, Ravi, Bender, Shawn B.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659692/
https://ncbi.nlm.nih.gov/pubmed/28977602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00416
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