Orthotopic Patient-Derived Xenografts of Pediatric Solid Tumors

Pediatric solid tumors arise from endodermal, ectodermal, or mesodermal lineages(1). Although the overall survival of children with solid tumors is 75%, that of children with recurrent disease is below 30%(2). To capture the complexity and diversity of pediatric solid tumors and establish new models...

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Pubblicato in:Nature
Autori principali: Stewart, Elizabeth, Federico, Sara M., Chen, Xiang, Shelat, Anang A., Bradley, Cori, Gordon, Brittney, Karlstrom, Asa, Twarog, Nathaniel R., Clay, Michael R., Bahrami, Armita, Freeman, Burgess B., Xu, Beisi, Zhou, Xin, Wu, Jianrong, Honnell, Victoria, Ocarz, Monica, Blankenship, Kaley, Dapper, Jason, Mardis, Elaine R., Wilson, Richard K., Downing, James, Zhang, Jinghui, Easton, John, Pappo, Alberto, Dyer, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659286/
https://ncbi.nlm.nih.gov/pubmed/28854174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23647
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