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Identification of Therapeutic Targets in Rhabdomyosarcoma Through Integrated Genomic, Epigenomic, and Proteomic Analyses

Personalized cancer therapy targeting somatic mutations in patient tumors is increasingly being incorporated into practice. Other therapeutic vulnerabilities resulting from changes in gene expression due to tumor specific epigenetic perturbations are progressively being recognized. These genomic and...

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Veröffentlicht in:Cancer Cell
Hauptverfasser: Stewart, Elizabeth, McEvoy, Justina, Wang, Hong, Chen, Xiang, Honnell, Victoria, Ocarz, Monica, Gordon, Brittney, Dapper, Jason, Blankenship, Kaley, Yang, Yanling, Li, Yuxin, Shaw, Timothy I., Cho, Ji-Hoon, Wang, Xusheng, Xu, Beisi, Gupta, Pankaj, Fan, Yiping, Liu, Yu, Rusch, Michael, Griffiths, Lyra, Jeon, Jongrye, Freeman, Burgess B., Clay, Michael R., Pappo, Alberto, Easton, John, Shurtleff, Sheila, Shelat, Anang, Zhou, Xin, Boggs, Kristy, Mulder, Heather, Yergeau, Donald, Bahrami, Armita, Mardis, Elaine R., Wilson, Richard K., Zhang, Jinghui, Peng, Junmin, Downing, James R., Dyer, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158019/
https://ncbi.nlm.nih.gov/pubmed/30146332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.07.012
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