Chargement en cours...
Population Exposure‐Response Modeling Supported Selection of Naloxegol Doses in Phase III Studies in Patients With Opioid‐Induced Constipation
Naloxegol is approved for the treatment of opioid‐induced constipation (OIC) in adults with chronic noncancer pain. Population exposure‐response models were developed using data from a phase II study comprising 185 adults with OIC. The weekly probability of response defined as having ≥3/week spontan...
Enregistré dans:
| Publié dans: | CPT Pharmacometrics Syst Pharmacol |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2017
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5658281/ https://ncbi.nlm.nih.gov/pubmed/28782266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12229 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|