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Population pharmacokinetics of naloxegol in a population of 1247 healthy subjects and patients
AIMS: Naloxegol, a polyethylene glycol conjugated derivative of the opioid antagonist naloxone, is in clinical development for treatment of opioid‐induced constipation (OIC). The aim of the study was to develop a population pharmacokinetic model describing the concentration vs. time profile of orall...
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| Pubblicato in: | Br J Clin Pharmacol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4693583/ https://ncbi.nlm.nih.gov/pubmed/26317320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12756 |
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