TRIM23 mediates virus-induced autophagy via activation of TBK1

Autophagy and interferon (IFN)-mediated innate immunity are critical antiviral defense mechanisms, and recent evidence indicated that tripartite motif (TRIM) proteins are important regulators of both processes. While the role of TRIM proteins in modulating antiviral cytokine responses has been well...

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Publicat a:Nat Microbiol
Autors principals: Sparrer, Konstantin M.J., Gableske, Sebastian, Zurenski, Matthew A., Parker, Zachary M., Full, Florian, Baumgart, Gavin J., Kato, Jiro, Pacheco-Rodriguez, Gustavo, Liang, Chengyu, Pornillos, Owen, Moss, Joel, Vaughan, Martha, Gack, Michaela U.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658249/
https://ncbi.nlm.nih.gov/pubmed/28871090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-017-0017-2
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