TRIM23 mediates virus-induced autophagy via activation of TBK1

Autophagy and interferon (IFN)-mediated innate immunity are critical antiviral defense mechanisms, and recent evidence indicated that tripartite motif (TRIM) proteins are important regulators of both processes. While the role of TRIM proteins in modulating antiviral cytokine responses has been well...

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Pubblicato in:Nat Microbiol
Autori principali: Sparrer, Konstantin M.J., Gableske, Sebastian, Zurenski, Matthew A., Parker, Zachary M., Full, Florian, Baumgart, Gavin J., Kato, Jiro, Pacheco-Rodriguez, Gustavo, Liang, Chengyu, Pornillos, Owen, Moss, Joel, Vaughan, Martha, Gack, Michaela U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658249/
https://ncbi.nlm.nih.gov/pubmed/28871090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-017-0017-2
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