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Non-redundant roles of keratinocyte-derived IL-34 and neutrophil-derived CSF1 in Langerhans cells renewal in the steady-state and skin inflammation

IL-34 and colony stimulating factor 1 (CSF1) are two alternative ligands for the CSF1 receptor that play non-redundant roles in the development, survival and function of tissue macrophages and Langerhans cells (LCs). In this study, we investigated the spatio-temporal production of IL-34 and its impa...

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Immunol
Hauptverfasser: Wang, Yaming, Bugatti, Mattia, Ulland, Tyler K., Vermi, William, Gilfillan, Susan, Colonna, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658206/
https://ncbi.nlm.nih.gov/pubmed/26634935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545917
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