IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

The differentiation of bone marrow–derived progenitors into monocytes, tissue macrophages and some dendritic cell (DC) subtypes requires the growth factor CSF1 and its receptor, CSF1R. Langerhans cells (LCs) and microglia develop from embryonic myeloid precursors that populate the epidermis and cent...

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Detalhes bibliográficos
Main Authors: Wang, Yaming, Szretter, Kristy J., Vermi, William, Gilfillan, Susan, Rossini, Cristina, Cella, Marina, Barrow, Alexander D., Diamond, Michael S., Colonna, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941469/
https://ncbi.nlm.nih.gov/pubmed/22729249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2360
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