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Interkeukin-34, a cytokine crucial for the differentiation and maintenance of tissue resident macrophages and Langerhans cells

IL-34 is a recently discovered cytokine that acts on tissue resident macrophages and Langerhans cells upon binding the receptor for CSF-1, CSF-1R. The existence of two ligands for CSF-1R, IL-34, and CSF-1, raises several intriguing questions. Are IL-34 and CSF-1 redundant or does each perform tempor...

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Detalles Bibliográficos
Main Authors: Wang, Yaming, Colonna, Marco
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137395/
https://ncbi.nlm.nih.gov/pubmed/24737461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344365
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