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IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
The differentiation of bone marrow–derived progenitors into monocytes, tissue macrophages and some dendritic cell (DC) subtypes requires the growth factor CSF1 and its receptor, CSF1R. Langerhans cells (LCs) and microglia develop from embryonic myeloid precursors that populate the epidermis and cent...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3941469/ https://ncbi.nlm.nih.gov/pubmed/22729249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2360 |
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