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Langerhans cells renew in the skin throughout life under steady-state conditions

Langerhans cells (LCs) are bone marrow (BM)–derived epidermal dendritic cells (DCs) that represent a critical immunologic barrier to the external environment, but little is known about their life cycle. Here, we show that in lethally irradiated mice that had received BM transplants, LCs of host orig...

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Pubblicato in:Nat Immunol
Autori principali: Merad, Miriam, Manz, Markus G., Karsunky, Holger, Wagers, Amy, Peters, Wendy, Charo, Israel, Weissman, Irving L., Cyster, Jason G., Engleman, Edgar G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727838/
https://ncbi.nlm.nih.gov/pubmed/12415265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni852
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