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Flk2(+) myeloid progenitors are the main source of Langerhans cells

Langerhans cells (LCs) are antigen-presenting cells (APCs) residing in the epidermis that play a major role in skin immunity. Our earlier studies showed that when skin is inflamed LCs are replaced by bone marrow-derived progenitor cells, while during steady-state conditions LCs are able to self-rene...

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Podrobná bibliografie
Hlavní autoři: Mende, Ines, Karsunky, Holger, Weissman, Irving L., Engleman, Edgar G., Merad, Miriam
Médium: Artigo
Jazyk:Inglês
Vydáno: © 2006 by The American Society of Hematology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895406/
https://ncbi.nlm.nih.gov/pubmed/16263793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-05-1878
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