Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease

Skin is the most commonly affected organ in graft-versus-host disease (GVHD). To explore the role of Langerhans cells in GVHD, the principal dendritic cells of the skin, we studied the fate of these cells in mice transplanted with allogeneic bone marrow. In contrast to other dendritic cells, host La...

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Detaylı Bibliyografya
Yayımlandı:Nat Med
Asıl Yazarlar: Merad, Miriam, Hoffmann, Petra, Ranheim, Erik, Slaymaker, Sarah, Manz, Markus G, Lira, Sergio A, Charo, Israel, Cook, Donald N, Weissman, Irving L, Strober, Samuel, Engleman, Edgar G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2004
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727841/
https://ncbi.nlm.nih.gov/pubmed/15098028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1038
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