Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease

Skin is the most commonly affected organ in graft-versus-host disease (GVHD). To explore the role of Langerhans cells in GVHD, the principal dendritic cells of the skin, we studied the fate of these cells in mice transplanted with allogeneic bone marrow. In contrast to other dendritic cells, host La...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Med
Autori principali: Merad, Miriam, Hoffmann, Petra, Ranheim, Erik, Slaymaker, Sarah, Manz, Markus G, Lira, Sergio A, Charo, Israel, Cook, Donald N, Weissman, Irving L, Strober, Samuel, Engleman, Edgar G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727841/
https://ncbi.nlm.nih.gov/pubmed/15098028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1038
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi