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Cardiovascular phenotype in Smad3 deficient mice with renovascular hypertension
Renovascular hypertension (RVH) has deleterious effects on both the kidney and the heart. TGF-β signaling through Smad3 directs tissue fibrosis in chronic injury models. In the 2-kidney 1-clip (2K1C) model of RVH, employing mice on the 129 genetic background, Smad3 deficiency (KO) protects the steno...
Tallennettuna:
| Julkaisussa: | PLoS One |
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| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5658153/ https://ncbi.nlm.nih.gov/pubmed/29073282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187062 |
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