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Genetic deficiency of Smad3 protects against murine ischemic acute kidney injury
TGF-β1 contributes to chronic kidney disease, at least in part, via Smad3. TGF-β1 is induced in the kidney following acute ischemia, and there is increasing evidence that TGF-β1 may protect against acute kidney injury. As there is a paucity of information regarding the functional significance of Sma...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154585/ https://ncbi.nlm.nih.gov/pubmed/21525133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00162.2011 |
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