Ccl2 deficiency protects against chronic renal injury in murine renovascular hypertension

Inflammation plays an important role in the pathogenesis of renal and cardiovascular disease in renovascular hypertension (RVH). Ccl2 is an important mediator of inflammation, and is induced within 24 hours following surgery to establish RVH in the murine 2 kidney 1 clip model, a time prior to onset...

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Publicado no:Sci Rep
Main Authors: Kashyap, Sonu, Osman, Mazen, Ferguson, Christopher M., Nath, Meryl C., Roy, Bhaskar, Lien, Karen R., Nath, Karl A., Garovic, Vesna D., Lerman, Lilach O., Grande, Joseph P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988825/
https://ncbi.nlm.nih.gov/pubmed/29872089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26870-y
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