Poly(ADP-ribose)polymerases inhibitors prevent early mitochondrial fragmentation and hepatocyte cell death induced by H(2)O(2)

Poly(ADP-ribose)polymerases (PARPs) are a family of NAD(+) consuming enzymes that play a crucial role in many cellular processes, most clearly in maintaining genome integrity. Here, we present an extensive analysis of the alteration of mitochondrial morphology and the relationship to PARPs activity...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Martín-Guerrero, Sandra M., Muñoz-Gámez, José A., Carrasco, María-Carmen, Salmerón, Javier, Martín-Estebané, María, Cuadros, Miguel A., Navascués, Julio, Martín-Oliva, David
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658148/
https://ncbi.nlm.nih.gov/pubmed/29073231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187130
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker